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Coexisting Juvenile Dermatomyositis and Sickle Cell Disease: Maintaining a High Degree of Suspicion

Ellen Fraint1, Maureen Leffler2, Corinna L Schultz3

  • 1Department of Pediatrics, Nemours/A.I. duPont Hospital for Children, Wilmington, DE.

The Journal of Pediatrics
|April 12, 2017
PubMed

Insights

Juvenile dermatomyositis, a childhood inflammatory myopathy, was diagnosed in an 11-year-old girl with sickle cell disease. This case highlights challenges in diagnosing and treating these co-occurring chronic conditions.

Area of Science:

  • Pediatric Rheumatology
  • Hematology

Background:

  • Sickle cell disease (SCD) is a prevalent inherited blood disorder.
  • Juvenile dermatomyositis (JDM) is a rare autoimmune disease affecting children.

Observation:

  • An 11-year-old female patient with a history of SCD presented with symptoms suggestive of JDM.
  • This represents a novel co-occurrence of these two distinct chronic conditions.

Findings:

  • The patient was diagnosed with both SCD and JDM.
  • Concurrent management of these diseases presented unique clinical hurdles.

Implications:

  • This case underscores the importance of considering autoimmune myopathies in children with SCD.
  • Further research is needed to understand the interplay between SCD and JDM and optimize treatment strategies.

Keywords:
hematologypainrheumatologyweakness

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