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Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Related Experiment Video

Updated: Apr 9, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Permanent Leadless Cardiac Pacemaker Therapy: A Comprehensive Review.

Fleur V Y Tjong1, Vivek Y Reddy2

  • 1From AMC Heart Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands (F.V.Y.T.); and Helmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, NY (V.Y.R.).

Circulation
|April 12, 2017
PubMed
Summary

Leadless pacemakers offer an alternative to traditional devices but have similar procedural complications. Further research is needed to determine their long-term effectiveness and optimal clinical use.

Keywords:
arrhythmias, cardiaccardiac pacing, artificialleadless pacingpacemaker, artificial

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Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Conventional transvenous pacemakers face lead- and pocket-related complications.
  • Leadless pacemaker therapy is a novel approach to cardiac pacing.
  • These devices are self-contained and implanted via a femoral percutaneous approach.

Purpose of the Study:

  • To review clinical data on leadless pacemakers.
  • To compare early leadless pacemaker results with historical conventional pacemaker data.
  • To assess the safety and efficacy of leadless pacing technology.

Main Methods:

  • Review of available clinical data on leadless pacemakers.
  • Comparison of short-term complication rates between leadless and conventional single-chamber pacemakers.
  • Analysis of implant procedure-related complications for leadless devices.

Main Results:

  • Leadless pacemakers show complications primarily related to the implant procedure, including cardiac perforation, dislocation, and vascular access site issues.
  • Short-term complication rates were slightly higher for leadless pacemakers (4.8%) compared to conventional pacemakers (4.1%).
  • Implanter learning curve significantly influences leadless pacemaker complication rates.

Conclusions:

  • Leadless pacemakers present an alternative therapy with similar early complication profiles to conventional pacing.
  • Long-term outcome data for leadless pacemakers are currently unavailable.
  • Future large-scale trials are necessary to establish the definitive role of leadless pacing and explore advanced multicomponent systems.