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[Diabetes and heart failure : Update 2017]
1Medizinische Klinik I - Kardiologie, Pneumologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum Aachen, RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland. kschuett@ukaachen.de.
Insights
Patients with diabetes mellitus have a higher risk of heart failure, which has a poor prognosis. Early diagnosis and specific therapies for heart failure in diabetes patients can significantly improve outcomes.
Area of Science:
- Cardiology
- Endocrinology
- Diabetology
Background:
- Diabetes mellitus significantly increases the risk of developing heart failure.
- Heart failure in diabetic patients is associated with a poor prognosis and increased mortality.
- Current cardiovascular strategies for diabetes primarily focus on preventing coronary events.
Purpose of the Study:
- To provide a comprehensive overview of heart failure in diabetes patients.
- To discuss the epidemiology, pathophysiology, and prognosis of heart failure in diabetes.
- To address current therapeutic strategies for heart failure in diabetes and vice versa.
Main Methods:
- Literature review and synthesis of current research findings.
- Analysis of epidemiological data on heart failure in diabetes.
- Review of pathophysiological mechanisms linking diabetes and heart failure.
- Evaluation of current therapeutic guidelines and emerging treatments.
Main Results:
- Diabetic patients face a substantially elevated risk of heart failure.
- Heart failure in this population portends a worse prognosis compared to non-diabetics.
- Emerging evidence highlights the importance of early heart failure diagnosis and tailored therapies.
- Therapeutic approaches require consideration of both conditions concurrently.
Conclusions:
- Heart failure is a critical complication of diabetes mellitus with significant prognostic implications.
- A shift towards early diagnosis and specific management strategies for heart failure in diabetes is warranted.
- Integrated therapeutic approaches addressing both diabetes and heart failure are essential for improving patient outcomes.
Abstract:
Patients with diabetes mellitus exhibit an increased risk for the development of heart failure. The occurrence of heart failure in patients with diabetes is associated with a poor prognosis. Therapeutic strategies to reduce cardiovascular morbidity and mortality in diabetes have so far mainly focused on the prevention of coronary events but recent data suggest that an early diagnosis of heart failure in diabetes as well as specific therapies could have a major impact on the prognosis for these patients. This article aims to provide a comprehensive overview on the epidemiology, pathophysiology and prognosis of heart failure in diabetes patients and addresses current aspects of heart failure therapy in diabetes as well as diabetes therapy in heart failure patients.