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Related Experiment Videos

Intraocular Metastases--A Review.

Lazaros Konstantinidis1, Bertil Damato2

  • 1Vitreoretinal Department, Jules Gonin University Eye Hospital, Lausanne, Switzerland.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|April 12, 2017
PubMed
Summary

Choroidal metastases, the most common intraocular malignancy, originate from breast and lung cancers. Diagnosis involves imaging and biopsy, with local therapies offering good responses despite poor initial life expectancy.

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Area of Science:

  • Ophthalmology
  • Oncology
  • Medical Imaging

Background:

  • Intraocular metastases are the most frequent intraocular malignancy, primarily affecting the uveal tract, especially the posterior choroid.
  • They often represent the initial clinical manifestation of systemic tumor dissemination.
  • Common primary sources include breast and lung cancers.

Purpose of the Study:

  • To review the clinical presentation, diagnosis, and management of choroidal metastases.
  • To highlight the importance of early detection and multimodal treatment strategies.
  • To discuss the prognostic factors and evolving therapeutic landscape.

Main Methods:

  • Review of clinical data and diagnostic modalities for intraocular metastases.
  • Discussion of treatment outcomes for local and systemic therapies.
Keywords:
choroidal metastasesintraocular metastasesuveal metastases

Related Experiment Videos

  • Analysis of patient survival and prognostic indicators.

    • Main Results:

    • Choroidal metastases typically present as creamy white or pale yellow masses with subretinal fluid, potentially multifocal and bilateral.
    • Ultrasonography and optical coherence tomography are key diagnostic tools.
    • Local therapies like radiation, photodynamic therapy, and transpupillary thermotherapy yield good responses when systemic treatment fails.

    Conclusions:

    • Choroidal metastases are a significant oncological challenge requiring prompt diagnosis and management.
    • While life expectancy is generally poor, therapeutic advances are improving patient outcomes.
    • Multidisciplinary care integrating ophthalmology and oncology is crucial for optimal patient management.