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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Updated: Jun 24, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Primary Pituitary Tuberculosis Revisited.

Fatma Ben Abid1, Mohammed Abukhattab1, Hanfa Karim1

  • 1Division of Infectious Disease, Department of Medicine, Hamad General Hospital, Doha, Qatar.

The American Journal of Case Reports
|April 13, 2017
PubMed
Summary
This summary is machine-generated.

Primary pituitary tuberculosis is rare and often misdiagnosed as pituitary adenoma. Early diagnosis and treatment with anti-tuberculous medications are crucial to prevent permanent dysfunction.

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Area of Science:

  • Endocrinology
  • Neurology
  • Infectious Diseases

Background:

  • Primary pituitary tuberculosis is an exceptionally rare condition, with fewer than 100 reported cases globally.
  • Misdiagnosis as pituitary adenoma is frequent, potentially leading to delayed treatment and severe complications.

Observation:

  • A middle-aged woman presented with severe headache and third cranial nerve palsy, indicative of a pituitary mass.
  • MRI revealed a large pituitary tumor with invasion into the cavernous sinus, initially presumed to be a pituitary adenoma.

Findings:

  • Histopathological examination of a pituitary biopsy confirmed tuberculosis as the cause.
  • Extensive investigations ruled out tuberculosis in other organs, identifying this as an isolated primary pituitary tuberculosis case.
  • The patient responded successfully to anti-tuberculous medication.

Implications:

  • In tuberculosis-endemic regions, pituitary tuberculosis must be considered in the differential diagnosis of pituitary tumors.
  • Considering pituitary tuberculosis can prevent unnecessary surgical interventions and improve patient outcomes.
  • This case highlights the importance of considering rare diagnoses in endemic areas and presents the first histologically proven case from Qatar.