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A Literature Revision in Primary Cutaneous B-cell Lymphoma
R La Selva1, S Alberti Violetti2, C Delfino3
1Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
Abstract:
The term "Primary Cutaneous B-Cell Lymphoma" (PCBCL) comprehends a variety of lymphoproliferative disorders characterized by a clonal proliferation of B-cells primarily involving the skin. The absence of evident extra-cutaneous disease must be confirmed after six-month follow-up in order to exclude a nodal non-Hodgkin's lymphoma (NHL) with secondary cutaneous involvement, which may have a completely different clinical behavior and prognosis. In this article, we have summarized the clinico-pathological features of main types of PCBCL and we outline the guidelines for management based on a review of the available literature.
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