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Updated: Aug 14, 2026
Optimization of Performance Parameters of the TAGGG Telomere Length Assay
Published on: April 21, 2023
Single-molecule imaging of telomerase activity via linear plasmon rulers
Guang-Sheng Qian1, Ting-Ting Zhang, Wei Zhao
1State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. weizhao@nju.edu.cn xujj@nju.edu.cn.
Abstract:
Plasmon rulers (PRs) exploit the potential of plasmon coupling between individual pairs of noble metal nanoparticles in biological processes, especially single-molecule detection. Herein, for the first time, we report a strategy based on Ag PRs for in situ monitoring of the extension process of telomerase primer (TSP) activated by a single telomerase.
