Related Experiment Videos
[Tumors of unknown origin: Case report].
Laeknabladid
|April 13, 2017
Summary
Immunoglobulin G4 (IgG4) related disease can affect multiple organs, presenting as inflammation or tumors. This case highlights successful treatment of recurrent IgG4 related disease with rituximab, achieving long-term remission.
Area of Science:
- Immunology
- Pathology
- Rheumatology
Background:
- Immunoglobulin G4 (IgG4) related disease is a chronic, fibrotic, and inflammatory condition characterized by IgG4-positive plasma cell infiltration.
- This disease can manifest as tumor-like lesions in virtually any organ, complicating diagnosis and treatment.
- Typical histopathological findings include lymphoplasmacytic infiltration, storiform fibrosis, and obliterative phlebitis.