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Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite
J D Herscheid1, R Wedzinga, W Verboom
1Radio-Nuclide-Centre (RNC), Free University, Amsterdam, The Netherlands.
Abstract:
The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described. For compounds with electron-donating substituents fair to good radiochemical yields have been reached.