Related Experiment Video
Updated: Aug 4, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Ebstein's Anomaly with Paradoxical Embolism to Lower Limb
Gouranga Santra1, Shinjan Patra2
1Associate Professor.
Ebstein's anomaly patients may experience paradoxical embolism (PDE) due to atrial septal defects. This case highlights limb ischemia from PDE in Ebstein's anomaly, emphasizing the need for early diagnosis to prevent severe outcomes.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Vascular Surgery
Background:
- Ebstein's anomaly (EA) is a rare congenital heart malformation.
- Atrial septal defects (ASD) are frequently associated with EA.
- Paradoxical embolism (PDE) can occur when a venous thrombus crosses an intracardiac shunt, such as an ASD.
Observation:
- An 18-year-old male with known Ebstein's anomaly presented with acute left lower limb ischemia.
- Diagnostic evaluation revealed a paradoxical embolism to the lower extremity.
- No concurrent signs or symptoms of cerebral embolism were noted.
Findings:
- Paradoxical embolism is a potential complication in patients with Ebstein's anomaly and associated ASD.
- The clinical presentation can manifest as peripheral limb ischemia.
- This case underscores the importance of considering PDE in EA patients with acute limb ischemia.
Implications:
- Increased clinical awareness for PDE in Ebstein's anomaly is crucial for timely diagnosis.
- Early recognition and management of PDE can prevent limb loss.
- This emphasizes the need for comprehensive evaluation in EA patients presenting with embolic events.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Pulmonary Embolism I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction

