Related Experiment Videos
Linezolid-induced optic neuropathy in XDR pulmonary TB: A case series
Anand Srivastava1, Silpa Kshetrimayum2, Sanjiv Kumar Gupta3
1Assistant Professor, Department of Respiratory Medicine, King George's Medical University, Lucknow, India.
Abstract:
Optic neuropathy has been reported as a side effect of long-term use of linezolid. This is particularly seen in cases of extensively drug resistant tuberculosis (XDR-TB) where treatment with linezolid may continue for about 24-30 months. We, hereby, report two cases of XDR-TB treated patients with a regimen containing linezolid who developed progressive painless loss of vision during the course of treatment. In both the cases, the visual symptoms resolved completely on withdrawing linezolid. Early recognition of this rare side effect and timely withdrawal may salvage the eyesight of such patients.