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Published on: January 18, 2011

Long-term non-invasive ventilation therapies in children: A scoping review

Maria L Castro-Codesal1, Kristie Dehaan2, Robin Featherstone3

  • 1Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Women & Children's Health Research Institute, University of Alberta, Edmonton, AB, Canada; Stollery Children's Hospital, Edmonton, AB, Canada.

Sleep Medicine Reviews
|April 16, 2017
PubMed

Insights

Long-term non-invasive ventilation (NIV) supports children with various respiratory disorders. While widely used, evidence quality varies, especially for less common conditions.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Critical Care

Background:

  • Long-term non-invasive ventilation (NIV) is a key respiratory support method for pediatric sleep and breathing disorders.
  • Understanding the scope of NIV application and research in children is crucial for clinical practice and future studies.

Purpose of the Study:

  • To conduct a scoping review summarizing the existing literature on long-term NIV use in pediatric populations.
  • To identify the range of conditions, study designs, and reported outcomes associated with pediatric NIV.

Main Methods:

  • Systematic literature search identifying 11,581 studies, with 289 included in the final analysis.
  • Analysis of study characteristics, reported medical conditions, data types, and outcome measures.

Main Results:

  • NIV is utilized across 73 pediatric conditions, most commonly obstructive sleep apnea and spinal muscular atrophy.
  • Studies predominantly featured single-center, observational, and retrospective designs with varying reporting of incidence, patient characteristics, and outcomes.
  • Adverse events and adherence were reported in 20% and 26% of studies, respectively.

Conclusions:

  • Long-term NIV is applied to a diverse pediatric patient population, but often supported by lower-quality evidence.
  • While robust data exist for common indications, further research is needed to support NIV use in many other conditions.

Keywords:
Artificial respirationContinuous positive airway pressurePediatricsRespiratory insufficiencyScoping reviewSleep apnea

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