Related Experiment Videos
Two new steroidal saponins isolated from Anemarrhena asphodeloides
Xing-Huan Sun1, Fu-Tao Zhu1, Yu-Wei Zhang1
1State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
Chinese Journal of Natural Medicines
|April 17, 2017
Abstract:
Two new steroidal saponins, named timosaponin P (1) and timosaponin Q (2), were isolated from the rhizome parts of Anemarrhena asphodeloides Bunge using various chromatographic methods. Their structures and absolute configurations were elucidated by a combination of spectroscopic and spectrometric data, including 1D, 2D NMR, HR-ESI-MS and ECD calculations, and this is the first time the absolute configuration of C-23 of steroidal saponin was confirmed by ECD calculations.