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Updated: Oct 9, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Epidemiology of the Small Renal Mass and the Treatment Disconnect Phenomenon

Robert M Turner1, Todd M Morgan2, Bruce L Jacobs3

  • 1Department of Urology, University of Pittsburgh Medical Center, Mercy Professional Building, 1350 Centre Avenue, Suite G100A, Pittsburgh, PA 15219, USA.

The Urologic Clinics of North America
|April 17, 2017
PubMed

Insights

Kidney cancer incidence is rising, often detected early due to imaging. Despite advances, mortality remains unchanged, indicating a need for better treatment strategies and risk factor reduction.

Area of Science:

  • Oncology
  • Public Health
  • Nephrology

Background:

  • Kidney cancer incidence has risen significantly in recent decades.
  • Early detection is common due to increased abdominal imaging, finding small, asymptomatic lesions.
  • Public health issues like smoking, hypertension, and obesity contribute to the rising incidence.

Purpose of the Study:

  • To analyze trends in kidney cancer incidence, detection, and mortality.
  • To investigate the impact of early detection and evolving treatment strategies.
  • To highlight the disconnect between earlier detection/treatment and unchanged mortality rates.

Main Methods:

  • Analysis of epidemiological data on kidney cancer incidence and mortality trends.
  • Review of diagnostic imaging practices and their impact on stage migration.
  • Examination of treatment modalities, including nephron-sparing approaches.
  • Assessment of the influence of public health factors on kidney cancer rates.

Main Results:

  • Most new kidney cancer cases are now detected at earlier, asymptomatic stages.
  • Despite earlier detection and increased use of nephron-sparing treatments, kidney cancer mortality rates have not decreased.
  • A significant portion of the increase in incidence is linked to smoking, hypertension, and obesity.

Conclusions:

  • There is a critical need to address the treatment disconnect in kidney cancer.
  • Reducing unnecessary treatment for indolent tumors is essential.
  • Targeting modifiable risk factors is crucial for decreasing both incidence and mortality of kidney cancer.
Keywords:
EpidemiologyIncidenceKidney cancerMortalityTreatment disconnect

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