Cerebral metastasis from malignant pulmonary fibrous histiocytoma. A case report

Within 3 months, a 13-year-old girl had two thoracotomies performed for resection of pulmonary primary and metastatic malignant fibrous histiocytoma (MFH). Seven months following the second operation, a right frontal cerebral metastasis was diagnosed as responsible for the sudden onset of a left hemiparesis. Although she recovered from the craniotomy, and tolerated radiation and chemotherapy, she succumbed 5 months later to recurrent pulmonary involvement. This case report uniquely records the spread of MFH to the brain in a child. The unusual appearance of this tumor in the pediatric age group and its rare presentation intracranially is explored within the context of the current pediatric literature.