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Updated: Oct 11, 2026
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Comparison of the measured pre-ejection periods and left ventricular ejection times between echocardiography and
Kazuki Noda1, Hideaki Endo1, Takahide Kadosaka1
1Department of Cardiology, Iwate Prefectural Central Hospital, Morioka 020-0066, Iwate, Japan.
Background:
The pre-ejection period (PEP) and left ventricular ejection time (LVET) are easily measured by impedance cardiography (ICG). We hypothesized that the PEP/LVET measured by ICG would correlate with that measured by echocardiography, and that PEP/LVET measured by ICG would be useful for cardiac resynchronization therapy (CRT) optimization.
Methods:
Newly CRT implanted patients were optimized by echocardiography. The PEP/LVET was measured by echocardiography and ICG in two different settings: optimized setting and right ventricle (RV)-only pacing.
Results:
The PEP/LVET was significantly decreased in the optimized setting compared with that in RV-only pacing (0.62±0.13 vs 0.75±0.16, p<0.05). The PEP/LVET values calculated by ICG and echocardiography were positively correlated (r=0.553, p=0.003).
Conclusion:
ICG was useful for the optimization of CRT.
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