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Radiogenomic Analysis of Oncological Data: A Technical Survey
Mariarosaria Incoronato1, Marco Aiello2, Teresa Infante3
1IRCCS SDN, Via E. Gianturco, 113, 80143 Naples, Italy. mincoronato@sdn-napoli.it.
International Journal of Molecular Sciences
|April 19, 2017
Summary
Radiogenomics combines imaging features with gene expression data for advanced cancer insights. This review explores cutting-edge techniques in radiomics and genomics for improved cancer diagnosis and treatment strategies.
Area of Science:
- Biomedical research
- Computational biology
- Medical imaging
Background:
- Biomedical research generates vast, complex datasets, including genetic and radiomic information.
- Radiogenomics integrates imaging features with gene expression data.
- Advanced analytical techniques are crucial for extracting meaningful insights from complex data.
Purpose of the Study:
- To review state-of-the-art techniques in radiomics and genomics.
- To focus on analysis methods using molecular and multimodal probes.
- To discuss the impact of these techniques in oncologic research.
Main Methods:
- Review of current radiomics and genomics analysis techniques.
- Focus on methods utilizing molecular and multimodal probes.
- Analysis of data from imaging and gene expression.
Main Results:
- Radiogenomics leverages non-conventional data analysis for cancer decision support.
- Techniques are being developed to correlate imaging features with gene expression.
- The impact of single and combined techniques on oncologic diseases is under investigation.
Conclusions:
- Radiogenomics offers powerful tools for cancer diagnosis and treatment.
- Further research is needed to fully understand the potential of integrated radiomic and genomic approaches.
- Advanced analytical methods are key to unlocking the full potential of radiogenomics in oncology.