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[A rare concurrence of polymyalgia rheumatica and AA-amyloidosis]

S G Radenska-Lopovok1, O N Kotenko2, N F Frolova2

  • 1I.M. Sechenov First Moscow State Medical University, Moscow, Russia; Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, Moscow, Russia.

Arkhiv Patologii
|April 19, 2017
PubMed

Insights

Polymyalgia rheumatica (PMR), a rare inflammatory condition affecting the elderly, can rarely lead to AA amyloidosis. This case highlights a patient with PMR who developed secondary AA amyloidosis, an uncommon complication.

Area of Science:

  • Rheumatology
  • Nephrology
  • Pathology

Background:

  • Polymyalgia rheumatica (PMR) is a rare chronic inflammatory disorder primarily affecting older adults.
  • PMR presents with gradual onset of shoulder and pelvic girdle muscle pain and stiffness, often accompanied by systemic symptoms like fever and weight loss.
  • While kidney involvement and AA amyloidosis are rare in PMR, giant cell arteritis co-occurs in approximately 25% of cases.

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