Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Applying the design-build-test paradigm in microbiome engineering.

Hoang Long Pham1, Chun Loong Ho1, Adison Wong1

  • 1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 117596, Singapore; NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Life Sciences Institute, National University of Singapore, 117456, Singapore.

Current Opinion in Biotechnology
|April 19, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Birth Weight Percentiles and Infant and Child Growth Dynamics.

JAMA network open·2026
Same authorSame journal

Microbial C1 assimilation pathways for chemical synthesis: from native metabolism to synthetic design.

Current opinion in biotechnology·2026
Same author

Abdominal fat distribution phenotypes and metabolic risk in premenopausal Asian women: insights beyond general adiposity measures.

Scientific reports·2026
Same author

Corrigendum to "Early childhood sleep practices, patterns, and awareness of guidelines in Singaporean parents and children" [Sleep Med 145 (2026) 109015].

Sleep medicine·2026
Same author

A framework for building a synthetic cell from the SynCell Asia Initiative.

Nature biotechnology·2026
Same author

Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.

Nature communications·2026
Same journal

Unlocking the biotechnological potential of traditional fermented food microbiomes.

Current opinion in biotechnology·2026
Same journal

Upcycling food processing byproducts via advanced yeast fermentation.

Current opinion in biotechnology·2026
Same journal

Medicinal plants fermentation: current knowledge and perspectives.

Current opinion in biotechnology·2026
Same journal

Fermented foods: lessons learned from metagenomics.

Current opinion in biotechnology·2026
Same journal

Microfluidic platforms for the transient transfection of mammalian cells: recent developments and challenges.

Current opinion in biotechnology·2026
See all related articles

Human microbiome engineering aims to improve health by modifying gut bacteria. This review covers design, methods, and analysis for effective microbiome engineering strategies.

Area of Science:

  • Microbiology
  • Biotechnology
  • Genomics

Background:

  • The human microbiome plays crucial roles in health and disease.
  • Recent discoveries have spurred interdisciplinary efforts to engineer the microbiome for therapeutic benefits.

Purpose of the Study:

  • To review recent advancements in human microbiome research.
  • To discuss the implications of microbiome modifications for human health.
  • To explore the application of a 'design-build-test' framework for microbiome engineering.

Main Methods:

  • Literature review of current research in microbiome engineering.
  • Analysis of design principles for engineering the human microbiome.
  • Examination of methods for conferring desired functions to the microbiome.

Related Experiment Videos

  • Evaluation of analytical techniques for complex microbiome samples.

    • Main Results:

    • Recent progress in understanding microbiome functions and their health implications.
    • Identification of key aspects for microbiome engineering: design, construction, and analysis.
    • The 'design-build-test' framework offers a structured approach to expedite engineering efforts.

    Conclusions:

    • Microbiome engineering holds significant potential for improving human health.
    • A systematic 'design-build-test' approach is crucial for advancing microbiome engineering.
    • Further research integrating design, functional modification, and analytical techniques is needed.