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Nutrition and High-Flow Nasal Cannula Respiratory Support in Children With Bronchiolitis
Katherine N Slain1, Natalia Martinez-Schlurmann2, Steven L Shein3
1Rainbow Babies & Children's Hospital, Cleveland, Ohio; and katherine.slain@uhhospitals.org.
Insights
Enteral nutrition in children with bronchiolitis on high-flow nasal cannula (HFNC) support is safe, with feeding-related adverse events occurring rarely. Early feeding initiation in these pediatric patients may lead to shorter hospital stays and reduced HFNC use.
Area of Science:
- Pediatrics
- Critical Care Medicine
- Neonatology
Background:
- Guidelines for initiating enteral nutrition in pediatric patients with bronchiolitis on high-flow nasal cannula (HFNC) support are lacking.
- Feeding-related adverse events (AEs) are a concern in this vulnerable population.
Purpose of the Study:
- To investigate the association between HFNC support and feeding-related AEs in children with bronchiolitis.
- To evaluate the impact of feeding timing on clinical outcomes.
Main Methods:
- A retrospective study of pediatric intensive care unit (PICU) patients (≤24 months) with bronchiolitis receiving HFNC.
- Data collected included demographics, respiratory support during feeding, and feeding-related AEs (respiratory distress, emesis).
- Feeding routes and HFNC delivery levels were documented across nursing shifts.
Main Results:
- Feeding-related AEs were rare (5.8% of feeding shifts) and not significantly associated with HFNC support levels (P = .092).
- Children initiated with early feeding (within 2 shifts) had a shorter PICU length of stay (2.2 vs 3.2 days, P = .006).
- Early feeding was also associated with a shorter duration of HFNC use (26.0 vs 53.5 hours, P = .002).
Conclusions:
- Feeding-related AEs are infrequent and not linked to the level of respiratory support in children with bronchiolitis on HFNC.
- Early enteral nutrition initiation in this cohort appears safe and may improve clinical outcomes, including reduced PICU stay and HFNC duration.
Objectives:
No guidelines are available regarding initiation of enteral nutrition in children with bronchiolitis on high-flow nasal cannula (HFNC) support. We hypothesized that the incidence of feeding-related adverse events (AEs) would not be associated with HFNC support.
Methods:
This retrospective study included children ≤24 months old with bronchiolitis receiving HFNC in a PICU from September 2013 through April 2014. Data included demographics, respiratory support during feeding, and feeding-related AEs. Feeding-related AEs were extracted from nursing documentation and defined as respiratory distress or emesis. Feed route and maximum HFNC delivery were recorded in 8-hour shifts (6 am-2 pm, 2 pm-10 pm, and 10 pm-6 am).
Results:
70 children were included, with a median age of 5 (interquartile range [IQR] 2-10) months. HFNC delivery at feed initiation varied widely, and AEs related to feeding occurred rarely. Children were fed in 501 of 794 (63%) of nursing shifts, with AEs documented in only 29 of 501 (5.8%) of those shifts. The incidence of AEs at varying levels of respiratory support did not differ (P = .092). Children in the "early feeding" (fed within first 2 shifts) group (n = 22) had a shorter PICU length of stay (2.2 days [IQR 1.4-3.9] vs 3.2 [IQR 2.5-5.3], P = .006) and shorter duration of HFNC use (26.0 hours [IQR 15.8-57.0] vs 53.5 [IQR 37.0-84.8], P = .002), compared with children in the "late feeding" group (n = 48).
Conclusions:
In this small, single-institution patient cohort, feeding-related AEs were rare and not related to the delivered level of respiratory support.
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