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Related Experiment Video

Updated: Jan 11, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Functional Morbidity Within 12 Months Following PICU Discharge Using Validated Screening Tools.

Debra J Rosenbaum¹, Nori M Minich^2,3, Rajashri Rasal²

¹Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, California.

Hospital Pediatrics

|November 11, 2025

Summary

This summary is machine-generated.

Pediatric intensive care unit (PICU) survivors face acquired dysfunction, with 13% affected one month post-discharge. Invasive mechanical ventilation (IMV) significantly increases this risk, and many children do not fully recover within a year.

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Area of Science:

Pediatric critical care medicine
Neurodevelopmental outcomes
Pediatric intensive care unit (PICU) research

Background:

Acquired dysfunction following critical illness can impact children's development.
Understanding the prevalence, trajectory, and risk factors is crucial for early intervention.
Validated screening tools are essential for accurate assessment.

Purpose of the Study:

To characterize the prevalence and trajectory of acquired dysfunction in children after PICU discharge.
To identify risk factors associated with acquired dysfunction compared to pre-illness status.
To utilize age-appropriate, validated screening tools for comprehensive assessment.

Main Methods:

Prospective, single-center study of children aged 1 month to 17 years admitted to the PICU.
Pre-illness baseline developmental status assessed using validated tools.
Follow-up assessments at 1, 6, and 12 months post-PICU discharge.

Main Results:

13% of children exhibited acquired dysfunction at 1 month post-discharge.
Invasive mechanical ventilation (IMV) was a significant risk factor (OR 2.72).
35% of patients showed persistent acquired dysfunction at last assessment.

Conclusions:

Approximately 1 in 8 children experience acquired dysfunction after PICU discharge.
Children receiving IMV have a substantially higher risk of acquired dysfunction.
Most children do not fully return to baseline function within 6-12 months post-PICU.