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Updated: Mar 3, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
Recent advances in boronic acid-based optical chemosensors
Xin Wu1, Xuan-Xuan Chen, Yun-Bao Jiang
1Department of Chemistry, College of Chemistry and Chemical Engineering, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, and iChEM, Xiamen University, Xiamen 361005, China. ybjiang@xmu.edu.cn.
Boronic acids form reversible bonds with polyols and bases, enabling robust chemosensors. Recent advances in sensing strategies and targets have improved performance for cell biology and catalysis.
Area of Science:
- Chemistry
- Biochemistry
- Materials Science
Background:
- Boronic acids reversibly bind to polyols and Lewis bases.
- This interaction is key for developing chemosensors for biologically relevant species.
- Previous research has established boronic acid-based molecular recognition.
Purpose of the Study:
- To review advances in boronic acid-based chemosensors from 2014-2016.
- To highlight new boron-containing binding motifs and analytical targets.
- To discuss novel sensing strategies and their impact on sensor performance.
Main Methods:
- Review of scientific literature from 2014-2016.
- Analysis of new boron-containing binding motifs.
- Examination of unconventional sensing strategies like nanoscale self-assembly and dynamic covalent assembly.
Main Results:
- Expansion of boronic acid utility through new motifs and targets.
- Significant sensor performance improvements via unconventional strategies.
- Demonstration of real-world applications in cell biology and asymmetric catalysis.
Conclusions:
- Boronic acid-based chemosensors have advanced significantly.
- Novel strategies enhance sensor performance for practical applications.
- These sensors are valuable tools in diverse scientific fields.
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