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Published on: August 16, 2024
An aggregation-induced electrochemiluminescence sensor for ochratoxin A detection integrating CRISPR-Cas12a and
Zhi-Hong Xu1, Xin Weng1, Meng-Ping Zhang2
1College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. 2012029@fjtcm.edu.cn.
The Analyst
|August 10, 2026
Abstract:
An aggregation-induced electrochemiluminescence (AIECL) biosensor combining CRISPR-Cas12a and tetrahedral DNA nanostructures (TDNs) is fabricated for OTA detection, with polymer dots (Pdots) serving as emitters. The sensor achieves favorable analytical performance, with a limit of detection of 0.41 pg mL-1, showing promising applications in food security monitoring.
