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Improved High-Quality Draft Genome Sequence and Annotation of Burkholderia contaminans LMG 23361T

Ji Young Jung1, Youngbeom Ahn1, Ohgew Kweon1

  • 1Division of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, USA.

Genome Announcements
|April 22, 2017
PubMed

Insights

This study presents the high-quality genome sequence of Burkholderia contaminans LMG 23361, a bacterium capable of biodegrading the disinfectant benzalkonium chloride (BZK). This genomic data aids in understanding BZK inactivation mechanisms.

Area of Science:

  • Microbiology
  • Genomics
  • Environmental Science

Background:

  • Burkholderia contaminans LMG 23361 is the type strain, isolated from mastitic sheep milk.
  • This strain demonstrates high biodegradation rates for benzalkonium chloride (BZK), a common disinfectant.
  • Understanding the genetic basis of BZK inactivation is crucial for environmental and pharmaceutical applications.

Purpose of the Study:

  • To generate an improved, high-quality draft genome sequence of Burkholderia contaminans LMG 23361.
  • To provide genomic resources for studying the biodegradation of benzalkonium chloride (BZK).

Main Methods:

  • High-quality draft genome sequencing of Burkholderia contaminans LMG 23361.
  • Bioinformatic analysis of the obtained genome sequence.

Main Results:

  • An improved high-quality draft genome sequence of Burkholderia contaminans LMG 23361 was successfully generated.
  • The genome sequence provides a foundation for identifying genes and pathways involved in BZK biodegradation.

Conclusions:

  • The availability of this high-quality genome sequence facilitates further research into the BZK inactivation capabilities of Burkholderia contaminans.
  • This genomic data can contribute to developing strategies for managing BZK in environmental and clinical settings.

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