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Updated: Mar 3, 2026

Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis
Published on: August 2, 2013
Epiretinal membrane negative staining and double peeling in a single block with Brilliant Blue G
1Ophthalmology Department, Setúbal Hospital Centre, Setúbal - Portugal.
Purpose:
To describe a surgical technique for combined peeling of epiretinal and internal limiting membranes.
Methods:
The authors present their procedure of choice for epiretinal membrane surgery: negative staining effect using Brilliant Blue G and single block removal of the epiretinal and internal limiting membranes in a single step.
Results:
A total of 26 eyes were operated with the described technique. In all cases, the peeling was performed successfully and with no complications. Minimum postoperative follow-up was 12 months. There were no recurrences of epiretinal membranes.
Conclusions:
The ideal surgical approach for epiretinal membranes should attempt to reduce mechanical trauma, light exposure, and dye toxicity.
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