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Technical and instrumentational foundations of PET/MRI
Ivo Rausch1, Harald H Quick2, Jacobo Cal-Gonzalez1
1Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
European Journal of Radiology
|April 23, 2017
Summary
Combined positron emission tomography (PET) and magnetic resonance imaging (MRI) whole-body systems, introduced in 2010, offer advanced disease exploration for personalized medicine. This paper details their origins, technical challenges, and clinical integration.
Area of Science:
- Medical Imaging
- Radiology
- Nuclear Medicine
Background:
- Combined positron emission tomography (PET) and magnetic resonance imaging (MRI) systems emerged for human applications in 2010.
- These systems integrate two powerful imaging modalities to overcome individual limitations.
- Significant technical and methodological challenges were addressed during their development.
Purpose of the Study:
- To highlight the origins and evolution of combined PET/MRI whole-body systems.
- To introduce the fundamental principles of PET and MRI as individual modalities.
- To discuss the technical and methodological hurdles in creating integrated PET/MRI systems.
- To underscore the potential of PET/MRI in advancing disease exploration and personalized medicine.
Main Methods:
- Review of the historical development of combined PET/MRI technology.
- Explanation of basic principles underlying PET and MRI.
- Discussion of engineering and data acquisition challenges in system integration.
- Overview of technical solutions enabling combined PET/MRI functionality.
Main Results:
- Combined PET/MRI systems are now clinically available after years of development.
- Fully integrated systems represent a significant advancement in multi-modality imaging.
- These systems have overcome initial technical and methodological barriers.
Conclusions:
- Combined PET/MRI represents a powerful tool for comprehensive disease investigation.
- The technology supports the long-term goal of personalized medicine through advanced diagnostics.
- Further exploration of PET/MRI methodology and technical solutions is crucial for clinical impact.
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