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Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

673
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

798
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Infective endocarditis in octogenarians.

Léopold Oliver1,2, Cécile Lavoute2, Roch Giorgi3,4

  • 1Aix-Marseille Université, Marseille, France.

Heart (British Cardiac Society)
|April 23, 2017
PubMed
Summary
This summary is machine-generated.

Infective endocarditis (IE) in octogenarians presents unique challenges, with higher mortality and specific microbial patterns. Surgical intervention, though underutilized, offers excellent survival rates for elderly patients with IE.

Keywords:
elderlyguidelinesinfective endocarditisoctogenarianssurgery

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Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Infectious Diseases

Background:

  • Infective endocarditis (IE) poses a significant health challenge, particularly in elderly populations.
  • Understanding the specific characteristics and outcomes of IE in octogenarians is crucial for optimizing treatment strategies.

Purpose of the Study:

  • To delineate the clinical features of infective endocarditis (IE) in patients aged 80 and above.
  • To evaluate the prognostic factors and outcomes, including mortality, associated with IE in this demographic.

Main Methods:

  • A prospective study included 454 patients with definite IE, categorized into three age groups: <65, 65-80, and ≥80 years.
  • The primary endpoint assessed was 1-year mortality, with secondary analyses focusing on microbial agents, complications, and surgical interventions.

Main Results:

  • Octogenarians (≥80 years) exhibited a significantly higher 1-year mortality rate (37.3%) compared to younger groups.
  • Enterococci and Streptococcus gallolyticus were the predominant microorganisms. Complications like embolism and renal failure were more frequent in the octogenarian group.
  • Despite a theoretical indication for surgery in 38 octogenarians, only 16 underwent the procedure. Operated patients had low mortality (6.3%), while non-operated patients faced very high mortality (72.7%).

Conclusions:

  • Infective endocarditis in octogenarians is distinct, characterized by specific pathogens and increased mortality.
  • Surgical intervention for IE in octogenarians, though less frequently implemented, is associated with excellent survival rates, suggesting it may be underused.
  • The poor prognosis in non-operated octogenarians with a surgical indication highlights the critical need to reconsider surgical candidacy in this age group.