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Updated: Mar 3, 2026
Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Memory assessment in patients with temporal lobe epilepsy to predict memory impairment after surgery: A systematic
P Parra-Díaz1, N García-Casares2
1Departamento de Medicina, Facultad de Medicina, Universidad de Málaga, Málaga, España.
Introduction:
Given that surgical treatment of refractory mesial temporal lobe epilepsy may cause memory impairment, determining which patients are eligible for surgery is essential. However, there is little agreement on which presurgical memory assessment methods are best able to predict memory outcome after surgery and identify those patients with a greater risk of surgery-induced memory decline.
Objective:
We conducted a systematic literature review to determine which presurgical memory assessment methods best predict memory outcome.
Material And Methods:
The literature search of PubMed gathered articles published between January 2005 and December 2015 addressing pre- and postsurgical memory assessment in mesial temporal lobe epilepsy patients by means of neuropsychological testing, functional MRI, and other neuroimaging techniques. We obtained 178 articles, 31 of which were included in our review.
Results:
Most of the studies used neuropsychological tests and fMRI; these methods are considered to have the greatest predictive ability for memory impairment. Other less frequently used techniques included the Wada test and FDG-PET.
Conclusions:
Current evidence supports performing a presurgical assessment of memory function using both neuropsychological tests and functional MRI to predict memory outcome after surgery.
