Related Experiment Video
Updated: Mar 3, 2026

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant
Emmett E Whitaker1,2, Veronica Miler1,2, Jason Bryant1,2
1Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital.
Insights
Severe complications like cardiac arrest can occur during general anesthesia in infants. Spinal anesthesia is explored as a safer alternative, particularly for urologic surgery, to mitigate risks and potential neurocognitive impacts.
Area of Science:
- Pediatric Anesthesiology
- Neurosurgery
- Urologic Surgery
Background:
- General anesthesia in infants carries risks of severe perioperative complications, including cardiac arrest.
- Emerging evidence suggests anesthetic agents may impact long-term neurocognitive outcomes in children.
- There is a growing interest in alternative anesthetic techniques to general anesthesia.
Observation:
- A case of infant cardiac arrest during general anesthesia for urologic surgery is presented.
- Spinal anesthesia was considered and utilized for subsequent anesthetic management.
- This case highlights the potential for severe adverse events under general anesthesia in pediatric patients.
Findings:
- The case demonstrates a critical event during general anesthesia requiring intervention.
- Spinal anesthesia was successfully employed as an alternative anesthetic approach.
- Review of perioperative risks associated with general anesthesia is crucial.
Implications:
- Spinal anesthesia may offer a safer alternative to general anesthesia in specific infant surgical cases.
- Understanding etiologic factors of perioperative complications is vital for patient safety.
- Further research into neurocognitive effects of different anesthetic agents is warranted.
Abstract:
Although generally safe and effective, severe perioperative complications, including cardiac arrest, may occur during general anesthesia in infants. With the emergence of evidence that specific anesthetic agents may affect future neurocognitive outcomes, there has been an increased focus on alternatives to general anesthesia, including spinal anesthesia. We present a case of cardiac arrest during general anesthesia in an infant who required urologic surgery. During the subsequent anesthetic care, spinal anesthesia was offered as an alternative to general anesthesia. The risks of severe perioperative complications during general anesthesia are reviewed, etiologic factors for such events are presented, and the use of spinal anesthesia as an alternative to general anesthesia is discussed.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview
Stages of General Anesthesia
Cardiopulmonary Resuscitation IV: Pharmacological Management

