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The osteo-odonto-keratoprosthesis.

Mehran Zarei-Ghanavati1, Venkata Avadhanam, Alfonso Vasquez Perez

  • 1aSussex Eye Hospital, Brighton, UK bFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran cBrighton and Sussex Medical School, Brighton dTongdean Eye Clinic, Hove, UK.

Current Opinion in Ophthalmology
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The osteo-odonto-keratoprosthesis is a key surgical option for corneal blindness in end-stage ocular surface disease. Recent advancements focus on managing complications like laminar resorption and improving optical outcomes.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Corneal blindness significantly impacts quality of life.
  • Ocular surface disease presents complex challenges for visual rehabilitation.
  • The osteo-odonto-keratoprosthesis (OOKP) offers a unique solution for severe cases.

Purpose of the Study:

  • To review the current practice of osteo-odonto-keratoprosthesis.
  • To highlight recent advancements in OOKP techniques and management.
  • To differentiate OOKP from other keratoprosthesis options.

Main Methods:

  • Review of literature on osteo-odonto-keratoprosthesis.
  • Description of surgical techniques and materials.
  • Analysis of recent developments in complication management and adjunctive therapies.

Main Results:

  • Psychological support is an integral part of OOKP care.
  • Innovations include sub-aqua lamina fashioning, thicker laminae, bisphosphonates, and advanced imaging for laminar resorption.
  • New approaches address buccal membrane overgrowth, glaucoma management, and posterior segment evaluation.

Conclusions:

  • Osteo-odonto-keratoprosthesis is the preferred choice for severe corneal blindness.
  • It serves a distinct patient population compared to Boston Type 1 KPro.
  • Ongoing developments enhance OOKP's efficacy and patient outcomes.