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Clickotine, A Personalized Smartphone App for Smoking Cessation: Initial Evaluation.

Brian M Iacoviello1,2, Joshua R Steinerman1, David B Klein1

  • 1Click Therapeutics, Inc., New York, NY, United States.

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|April 27, 2017
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This study shows that the Clickotine smartphone app for smoking cessation had high user engagement and encouraging quit rates. Future research should confirm its effectiveness in a randomized controlled trial.

Keywords:
cigarette smokingsmartphonesmoking cessationtherapeuticstobacco

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Area of Science:

  • Digital Health
  • Behavioral Science
  • Public Health

Background:

  • Smoking cessation is a major public health challenge with significant economic burden.
  • Effective interventions are limited by access and adherence issues.
  • Smartphone apps offer a scalable solution, but few align with clinical guidelines and have been rigorously tested.

Purpose of the Study:

  • To assess the engagement, efficacy, and safety of the Clickotine smartphone app for smoking cessation.
  • Evaluate user interaction metrics and self-reported abstinence rates.
  • Identify any adverse health events associated with app usage.

Main Methods:

  • Recruited US adults (18-65) who smoke daily and own an iPhone.
  • Utilized online advertising for recruitment and a web portal for consent and app download.
  • Collected baseline and 8-week assessment data via the online portal, ensuring secure data handling.

Main Results:

  • 416 participants downloaded the app; high engagement observed with an average of 100.6 app opens and 214.4 interactions.
  • After 8 weeks, 45.2% (ITT) and 51.5% (completers) reported 7-day point abstinence.
  • 26.2% (ITT) and 29.9% (completers) reported 30-day point abstinence; minimal adverse events reported.

Conclusions:

  • Clickotine demonstrated promising user engagement and self-reported smoking cessation rates in an initial trial.
  • The app appears safe, with adverse events primarily related to nicotine withdrawal.
  • Further investigation via a randomized controlled trial is recommended to confirm efficacy.