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Updated: Mar 3, 2026

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Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
Published on: September 18, 2019
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Specific single-molecule detection of glucose in a supramolecularly designed tunnel junction
Tomoaki Nishino1, Hiroshi Shiigi, Manabu Kiguchi
1Department of Chemistry, School of Science, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152-8551, Japan. tnishino@chem.titech.ac.jp.
Abstract:
Scanning tunneling microscopy tips were functionalized with a boronic acid derivative. In combination with a similarly modified substrate, the molecular tip forms a supramolecular complex selectively with a glucose molecule. The conductance of the resulting single complex allows one to achieve the specific single-molecule detection of glucose.

