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Health-Related Quality of Life of Nepalese Children With Leukemia Using Pediatric Quality of Life Inventory 4.0

Anu V K1, Mandira Onta2, Sarala Joshi2

  • 11 Shree Medical and Technical College, Chitwan, Nepal.

Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses
|April 28, 2017
PubMed

Insights

Health-related quality of life (HRQOL) in children with leukemia is crucial. This study found social functioning was highest and emotional functioning lowest, with age impacting HRQOL, highlighting the need for age-specific care.

Area of Science:

  • Pediatric Oncology
  • Health Services Research
  • Quality of Life Studies

Background:

  • Health-related quality of life (HRQOL) is vital for assessing the comprehensive impact of leukemia in children.
  • Understanding HRQOL in pediatric leukemia patients is essential for holistic care and treatment evaluation.

Purpose of the Study:

  • To evaluate the overall HRQOL and specific functioning in Nepalese children with leukemia using the PedsQL 4.0.
  • To compare self-reported HRQOL with parent proxy reports.
  • To identify factors influencing HRQOL in pediatric leukemia patients.

Main Methods:

  • A descriptive cross-sectional study involving 43 children with leukemia and their parents.
  • Utilized the culturally and linguistically validated Pediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL 4.0).
  • Data collected via interview schedule at B. P. Koirala Memorial Cancer Hospital, Bharatpur.

Main Results:

  • Both child self-reports and parent proxy reports indicated highest scores in social functioning and lowest in emotional functioning.
  • Intraclass correlation coefficients showed strong agreement for physical functioning (0.828) and weaker agreement for social functioning (0.493).
  • Age was significantly associated with total HRQOL scores and physical/emotional functioning subscales in proxy reports.

Conclusions:

  • Emotional functioning requires targeted interventions to improve pediatric leukemia patients' quality of life.
  • Addressing age-specific needs of children with leukemia is critical for enhancing their overall HRQOL.
  • Discrepancies between self- and proxy-reports highlight the importance of considering both perspectives in HRQOL assessments.

Keywords:
Nepalchildrenhealth-related quality of lifeleukemia

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