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Updated: Mar 3, 2026

Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice
Published on: September 28, 2022
[Retracted] Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury
Yunhu Yu1, Fang Cao2, Qishan Ran3
1Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.
Abstract:
We would like to retract our article entitled 'Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury' published in Molecular Medicine Reports 14: 5556-5566, 2016. After careful consideration, we recognize that there was an undeclared conflict of interest on the part of certain of the authors. All the authors agree to this retraction. We sincerely apologize for any inconvenience that might result from the retraction of this article. [The original article was published in Molecular Medicine Reports 14: 5556-5566, 2016; DOI: 10.3892/mmr.2016.5954].
Insights
This study on traumatic brain injury (TBI) in mice is retracted due to an undeclared author conflict of interest. The neuroprotective effects of regulatory T cells in TBI models are therefore withdrawn.
Area of Science:
- Neuroscience
- Immunology
- Cell Biology
Background:
- Traumatic brain injury (TBI) is a significant cause of mortality and disability.
- Regulatory T cells (Tregs) play a crucial role in immune regulation and have shown potential in various disease models.
Purpose of the Study:
- To investigate the neuroprotective effects of regulatory T cells in a mouse model of traumatic brain injury.
Main Methods:
- The study utilized a mouse model of TBI.
- Regulatory T cells were administered or analyzed in relation to TBI outcomes.
Main Results:
- The original article reported neuroprotective effects of regulatory T cells in TBI.
Conclusions:
- The findings of the original article are invalidated due to the retraction.

