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Updated: Mar 3, 2026

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
Published on: October 28, 2014
Cellular polyamines modulate mRNA stability
Haoxi Chai1, Wannian Yang2, Huazhong Shi1,2
1a Department of Chemistry and Biochemistry , Texas Tech University , Lubbock , TX , USA.
Abstract:
Polyamines (PAs) are polycationic compounds found in all living organisms and play crucial roles in growth and survival. PAs interact with and modulate the functions of anionic macromolecules such as DNA, RNA and proteins. LHR1/PUT3 is a polyamine influx transporter localized in the plasma membrane in Arabidopsis. In our recent paper in The Plant Journal, 1 we demonstrated that LHR1/PUT3 has a pivotal role in stabilizing the mRNAs of several important heat stress responsive genes under high temperature. In this short communication, we discuss about a putative pathway for modulating the PUT3 transport activity and the significance of evolutionary variations in PUT3 in Arabidopsis.
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