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Updated: Jul 26, 2026
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Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
Published on: March 9, 2017
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Activity-based assessment of an engineered hyperthermophilic protein as a capture agent in paper-based diagnostic
E A Miller1, M W Traxlmayr1, J Shen1
1Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
Molecular Systems Design & Engineering
|April 29, 2017
Abstract:
Antibodies have traditionally served as the affinity reagents of choice in point-of-care diagnostic biosensors. However, this class of proteins is not ideally suited for this use, being poorly characterized and prone to thermal denaturation. Here, we present an activity-based assessment of an alternative engineered binding protein in a cellulose-based assay.
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