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New Eudesmane Sesquiterpenoids from Salvia plebeia R. Br
Lie-Feng Ma1, Peng-Fei Wang1, Ji-Dong Wang2
1College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, P. R. China.
Abstract:
Three new sesquiterpenoids, salplebeones A - C (1 - 3), were isolated from the ethanol-soluble extract of the aerial part of Salvia plebeia R. Br. Their structures were established by detailed analysis of NMR and MS spectra. Salplebeone A was an eudesmane lactone, while salplebeones B and C were rare eudesmane sesquiterpenoids, containing 12,8-lactam groups. Antiproliferative activities of salplebeones A - C to myeloid leukemia cell lines were evaluated.
