Related Experiment Video
Updated: Mar 3, 2026

07:58
Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata
Published on: November 23, 2017
8.3K
A new treatment for frostbite sequelae; Botulinum toxin
Arne Johan Norheim1,2, James Mercer3,4,5, Frauke Musial1
1a The National Research Centre in Complementary and Alternative Medicine, NAFKAM, Department of Community Medicine, Faculty of Health Sciences , University of Tromsø - The Arctic University of Norway , Norway.
International Journal of Circumpolar Health
|April 29, 2017
Summary
Frostbite can cause lasting nerve damage and blood flow issues in soldiers. Botulinum toxin injections improved a soldier's hand function and cold sensitivity after severe frostbite.
Area of Science:
- Occupational health
- Neurology
- Vascular medicine
Background:
- Frostbite sequelae pose significant risks for soldiers in arctic environments, impacting their ability to perform duties.
- Occupational injuries like frostbite can lead to long-term sensory-motor disturbances and cold hypersensitivity.
Observation:
- A Caucasian male soldier experienced severe frostbite to both hands during a military winter exercise.
- Post-injury, he presented with impaired blood flow (angiography, thermography) and somatosensory nerve dysfunction (Quantitative Sensory Testing).
Findings:
- An off-label treatment using Botulinum toxin injections around the digital neurovascular bundles was administered.
- Following treatment, the soldier showed reduced cold sensitivity, improved blood flow, and enhanced somatosensory nerve function.
Implications:
- This case suggests Botulinum toxin may be a viable therapeutic option for managing frostbite sequelae.
- Successful treatment can potentially restore function, enabling soldiers to continue their military careers in challenging environments.

