Hepatic Transplants in Espirito Santo State, Brazil

Area of Science:

• Hepatology
• Transplant Surgery
• Clinical Outcomes Research

Background:

• The Meridional Hospital Liver Transplant Unit is the sole active center in Espírito Santo State, Brazil, operational since 2004.
• This unit serves a critical role in liver transplantation within the region.

Purpose of the Study:

• To analyze data from the initial 250 liver transplant procedures conducted by the Meridional Hospital team.
• Evaluate the outcomes and characteristics of early liver transplant cases.

Main Methods:

• A retrospective analysis of patient files from January 2005 to December 2015.
• Inclusion of all liver transplants and retransplants performed during the study period.

Main Results:

• 250 liver transplants (236 patients, 14 retransplants) were performed, with 72.4% of recipients being male, averaging 51.1 years old.
• Alcoholic cirrhosis was the primary indication (33.6%). Surgical reintervention occurred in 58 patients, with hepatic artery thrombosis a key factor for retransplants (40%).
• The 1-year survival rate was approximately 71%, with a mortality peak within 2 months post-transplant. Average ICU and hospital stays were 8.52 and 21.7 days, respectively.

Conclusions:

• The Meridional Hospital liver transplant unit demonstrates survival rates comparable to national centers (68-74% at 1-year).
• The unit achieves these results despite logistical challenges and donor shortages, highlighting its effectiveness.