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Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
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Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Synthesis of hydroxyapatite for biomedical applications.

Aleksandra Szcześ¹, Lucyna Hołysz¹, Emil Chibowski¹

¹Department of Physiscal Chemistry - Interfacial Phenomena, Faculty of Chemistry, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.

Advances in Colloid and Interface Science

|May 2, 2017

Summary

Hydroxyapatite (HA) shows promise for creating biocompatible bone implants and drug delivery systems. This review explores HA

Keywords:

Biomaterials Drug delivery system Hydroxyapatite Implant coating

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Area of Science:

Biomaterials Science
Biomedical Engineering
Materials Chemistry

Background:

Developing long-lasting implants and bone substitutes with excellent biocompatibility, bioactivity, and mechanical strength is crucial.
Minimizing immune rejection and achieving patient-specific, micrometer-level control in bone substitute structures are significant challenges.
Nontoxic, targeted drug delivery systems with controlled release kinetics and reduced side effects are highly sought after.

Purpose of the Study:

To review the use of hydroxyapatite (HA) in creating advanced biomaterials.
To explore HA-based scaffolds, bone substitutes, and implant coatings with enhanced biocompatibility, bioactivity, and mechanical properties.
To discuss the potential of HA as a platform for targeted drug delivery systems.

Main Methods:

Literature review of existing research on hydroxyapatite applications in biomedical fields.
Analysis of studies focusing on biologically inspired scaffolds and implant coatings.
Examination of drug delivery systems utilizing hydroxyapatite.

Main Results:

Hydroxyapatite (HA) is a key biomaterial due to its similarity to natural bone mineral.
HA facilitates the development of scaffolds and coatings with desirable biocompatibility, bioactivity, and mechanical strength.
HA demonstrates potential for creating effective, controlled drug delivery systems.

Conclusions:

Hydroxyapatite is a versatile material for fabricating bone substitutes, implants, and drug delivery systems.
Biologically inspired HA structures offer solutions for tissue regeneration and targeted therapies.
Further research into HA-based materials can address critical needs in regenerative medicine and drug delivery.