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Desmoplastic tricholemmoma in a dog
Mun Keong Kok1, James K Chambers1, Atsushi Dohata1
1Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
The Journal of Veterinary Medical Science
|May 2, 2017
Summary
A canine mass below the eye was diagnosed as desmoplastic tricholemmoma. Histopathology revealed characteristic tumor cell proliferation and immunohistochemical markers, confirming this rare skin tumor diagnosis in dogs.
Area of Science:
- Veterinary Pathology
- Dermatopathology
- Oncology
Background:
- Skin tumors are common in dogs, requiring accurate histopathological diagnosis.
- Tricholemmomas are benign follicular tumors, with desmoplastic variants being rare.
Observation:
- A 10-year-old mixed breed dog presented with a 0.8 cm mass below the left eye.
- Surgical excision and histopathological examination were performed.
Findings:
- Microscopic analysis showed tumor cells in lobules, nests, and cords within a desmoplastic stroma.
- Periodic acid-Schiff (PAS) staining was positive in most tumor cells.
- Immunohistochemistry revealed diffuse positivity for cytokeratin 15, cytokeratin 19, and CD 34.
Implications:
- The findings support the diagnosis of desmoplastic tricholemmoma in this canine case.
- This case contributes to the understanding of rare skin neoplasms in veterinary medicine.
- Accurate diagnosis is crucial for appropriate patient management and prognosis.
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