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Prolonged energy harvesting for ingestible devices
Phillip Nadeau1, Dina El-Damak1, Dean Glettig2
1Department of Electrical Engineering and Computer Science, and the Microsystems Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Nature Biomedical Engineering
|May 2, 2017
Summary
This study introduces a new ingestible galvanic cell that continuously powers electronic devices in the gastrointestinal tract for over six days. This breakthrough enables prolonged in vivo monitoring for improved patient care.
Area of Science:
- Biomedical Engineering
- Gastroenterology
- Wearable Technology
Background:
- Ingestible electronics offer advanced patient monitoring but face limitations in power capacity and duration.
- Existing in vivo power harvesting systems provide only short bursts of energy, limiting prolonged use.
- The gastrointestinal tract presents unique challenges for long-term electronic device power supply.
Purpose of the Study:
- To design and evaluate a novel energy-harvesting galvanic cell for continuous in vivo power supply.
- To assess the device's capacity for prolonged operation throughout the gastrointestinal tract.
- To enable continuous temperature sensing and wireless communication for ingestible electronic devices.
Main Methods:
- Development of a biocompatible galvanic cell for energy harvesting.
- In vivo testing in porcine models to evaluate device performance.
- Continuous monitoring of power output and device operation duration.
Main Results:
- The galvanic cell achieved an average power output of 0.23 μW/mm².
- Continuous power delivery was sustained for an average of 6.1 days.
- The device successfully powered in vivo temperature measurements.
Conclusions:
- The developed energy-harvesting galvanic cell provides a viable solution for prolonged powering of ingestible electronics.
- This technology can support the next generation of long-term gastrointestinal monitoring systems.
- The findings pave the way for broader deployment of ingestible devices in healthcare.

