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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

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Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
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Glucose Transporters01:27

Glucose Transporters

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Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
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Related Experiment Video

Updated: Mar 3, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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Congenital Diabetes Mellitus.

Ramona Mohora1, Silvia-Maria Stoicescu1

  • 1Department of Neonatology, Polizu Maternity, Bucharest, Romania.

Maedica
|May 3, 2017
PubMed
Summary

Neonatal diabetes is a rare diagnosis requiring complex management. This case highlights the need for multidisciplinary collaboration between obstetricians, neonatologists, and diabetes doctors for effective newborn care.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Neonatology

Background:

  • Neonatal diabetes mellitus (NDM) is a rare condition with significant management challenges.
  • Early diagnosis and intervention are crucial for improving outcomes in affected infants.
  • Effective management requires a coordinated approach from various medical specialists.

Purpose of the Study:

  • To describe the management of a newborn with diabetes mellitus in a maternity setting.
  • To emphasize the importance of a collaborative approach in handling rare neonatal cases.
  • To provide insights into the care protocols for suspected neonatal diabetes.

Main Methods:

  • Case analysis of a neonate diagnosed with diabetes mellitus.
  • Review of the diagnostic and management pathway.

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  • Interdisciplinary team collaboration involving obstetrics, neonatology, and diabetology.

    • Main Results:

    • Successful management of a rare case of neonatal diabetes.
    • Demonstrated the feasibility of effective collaboration among specialists.
    • Identified key elements for protocol development.

    Conclusions:

    • The rarity of neonatal diabetes necessitates specialized protocols.
    • Multidisciplinary collaboration is essential for optimal patient care.
    • Structured management plans can guide medical teams in similar cases.