Related Experiment Video
Updated: Mar 3, 2026

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Beyond Thrombus Detection: The Role of Multimodality Imaging Approach
Maria Chiara Todaro1, Giovanni Sirianni1, Lisa Innocenti2
1Department of Cardiology, Humanitas Gavazzeni Hospital, Via M. Gavazzeni 21, 24125 Bergamo, Italy.
A rare paraneoplastic syndrome presented with a left ventricular apical thrombus and pulmonary embolism. This unusual combination was the initial sign of an undiagnosed lung adenocarcinoma.
Area of Science:
- Cardiology
- Oncology
- Pulmonology
Background:
- Paraneoplastic syndromes are rare complications of cancer.
- Lung adenocarcinoma is a common malignancy with diverse presentations.
Observation:
- A patient presented with a left ventricular apical thrombus and pulmonary embolism.
- These cardiovascular and pulmonary events were the initial clinical manifestations.
Findings:
- The coexisting left ventricular apical thrombus and pulmonary embolism were indicative of an unrecognized lung adenocarcinoma.
- This case highlights an unusual paraneoplastic presentation.
Implications:
- Early recognition of rare paraneoplastic syndromes is crucial for timely cancer diagnosis.
- This case underscores the importance of considering malignancy in patients with unexplained thromboembolic events.
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