Simultaneous presentation of two noninflammatory lung diseases in an HIV-infected patient
Rafael Martínez-Girón1, Santiago Martínez-Torre2
1Departament of Anatomic Pathology, INCLINICA Foundation for Clinical, Pneumological and Carcinogenic Research, Calvo Sotelo, 16, 33007, Oviedo, Spain.
Abstract:
The simultaneous presentation of two noninflammatory pulmonary diseases, pulmonary alveolar proteinosis and Kaposi's sarcoma (Ks), in an HIV-infected patient, is described. A 29-year-old black race patient was admitted to the hospital because of general malaise, weight loss, dyspnea, chest pain, and cough with hemoptoic expectoration. Chest X-rays revealed a patchy bilateral alveolar pattern with a tendency toward the formation of condensations. The serological test revealed HIV positivity (CD4 counts of 393 cells/mm3). Because there was no response to the treatment course, a thoracic CT was performed, showing interlobular thickening with intralobular septal lines and ground glass opacities ("crazy-paving" pattern). An open lung biopsy was performed. Histopathological diagnosis of pulmonary alveolar proteinosis and pulmonary Ks was made.
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