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Updated: Mar 3, 2026

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
Responsive, Water-Soluble Europium(III) Luminescent Probes
Sergey Shuvaev1, Matthieu Starck1, David Parker1
1Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
Abstract:
The design principles, mechanism of action and performance of europium(III) complexes that serve as strongly emissive and responsive molecular probes in water are critically discussed. Examples of systems designed to assess pH, selected metal ions and anions, including chiral species, as well as selected small molecules and biopolymers are considered, and prospects evaluated for improved performance in more complex biological media such as in bio-fluids and within living cells. Modulation of the emission spectral form, lifetime and degree of circular polarisation can be used to quantify the spectral response and permit calibration.
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