Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

1.4K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.4K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

316
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
316
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

326
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
326
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

250
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
250
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

288
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
288
Anorexia Nervosa01:28

Anorexia Nervosa

1.6K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amylin Analogs: The Next Major Class of Weight Loss Therapy: A Review of Experimental Data and Early-Phase Clinical Trials.

Diabetes, obesity & metabolism·2026
Same author

Obesity Remission: A Missing Target in Contemporary Medicine.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2026
Same author

Community pharmacists' experiences and perspectives on GLP-1 receptor agonists for obesity management: a cross-sectional study in Ireland.

The International journal of pharmacy practice·2026
Same author

Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis.

BMJ (Clinical research ed.)·2026
Same author

Pain in People Living With Obesity: Baseline Multidimensional Profiles, Prevalence and Biopsychosocial Factors From a Cohort Study.

European journal of pain (London, England)·2026
Same author

Body weight categories and fat distribution in relation to all-cause mortality among adults with metabolic dysfunction-associated steatotic liver disease: a population-based analysis of NHANES, 2007-2018.

BMJ open·2026

Related Experiment Video

Updated: Mar 2, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K

Morbidity and mortality associated with obesity.

Mahmoud Abdelaal1,2, Carel W le Roux1,3,4, Neil G Docherty1,3

  • 1Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.

Annals of Translational Medicine
|May 9, 2017
PubMed
Summary

Obesity significantly increases morbidity and mortality risk, with cardiovascular disease and cancer posing the greatest threats. Tools like the King's Criteria and Edmonton Obesity Staging System aid in assessing and managing these risks.

Keywords:
Morbiditymortalityobesity

More Related Videos

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

28.0K
Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.8K

Related Experiment Videos

Last Updated: Mar 2, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K
Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

28.0K
Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.8K

Area of Science:

  • Clinical Medicine
  • Public Health
  • Epidemiology

Background:

  • Obesity is a major global health concern, leading to significant morbidity, reduced quality of life, and decreased life expectancy.
  • Complications arising from obesity contribute substantially to healthcare burdens and mortality rates worldwide.

Purpose of the Study:

  • To summarize key obesity-related co-morbidities and their prevalence.
  • To review classification and grading systems for assessing mortality risk in obese individuals.
  • To identify tools for quantifying morbidity and mortality risk in obesity care.

Main Methods:

  • Literature screening for assessment tools related to obesity co-morbidities.
  • Identification of domains contributing to morbidity and mortality in obesity.
  • Evaluation of specific criteria and staging systems for risk assessment.

Main Results:

  • Thirteen domains were identified as significant contributors to morbidity and mortality in obesity.
  • Cardiovascular disease (CVD) and cancer represent the leading causes of obesity-related mortality.
  • The King's Criteria and Edmonton Obesity Staging System (EOSS) are effective tools for monitoring patient mortality risk.

Conclusions:

  • Effective patient management and public health messaging are crucial for primary prevention of obesity complications.
  • Utilizing established criteria and staging systems can improve the detection and monitoring of mortality risk in obesity care.
  • Understanding the co-morbidities of obesity is essential for improving patient outcomes and public health strategies.