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Updated: Mar 2, 2026
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Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
283
What are the differences between older and younger patients with epididymitis?
Fukashi Yamamichi1,2, Katsumi Shigemura1,3, Soichi Arakawa1,4
1Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Investigative and Clinical Urology
|May 9, 2017
Summary
Older patients with epididymitis (EP) are more likely to have pyuria, a condition linked to fever. These findings suggest a need for age-specific guidelines in managing EP.
Area of Science:
- Urology
- Geriatrics
- Infectious Diseases
Background:
- Societal aging and rising antibiotic resistance necessitate re-evaluating established medical conditions.
- Epididymitis (EP) management may require age-specific considerations despite established etiological and therapeutic strategies.
Purpose of the Study:
- To investigate the impact of patient age on epididymitis (EP)-related symptoms and urine findings.
- To compare EP presentation in older versus younger patient cohorts.
Main Methods:
- Retrospective data collection from 308 patients across 7 hospitals in Hyogo, Japan.
- Analysis of correlations between age (older vs. younger), urine findings (pyuria, bacteriuria), and EP symptoms (fever).
- Multivariate analysis to identify significant associations.
Main Results:
- Older age (≥65 years) was significantly correlated with the presence of pyuria (p=0.0156).
- Pyuria was significantly associated with fever (≥37℃; p=0.0159).
- Older EP patients exhibited pyuria more frequently than younger patients.
Conclusions:
- Age significantly influences the presentation of epididymitis (EP), with older patients more prone to pyuria.
- Pyuria in EP correlates with fever, highlighting its clinical relevance in older individuals.
- The findings suggest the potential necessity for age-specific clinical guidelines for epididymitis (EP) management.
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