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  1. Home
  2. Incidence And Risk Factors For Perioperative Infections After Robot-assisted Radical Prostatectomy: A Multicenter Study.
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  2. Incidence And Risk Factors For Perioperative Infections After Robot-assisted Radical Prostatectomy: A Multicenter Study.

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Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Incidence and Risk Factors for Perioperative Infections After Robot-Assisted Radical Prostatectomy: A Multicenter

Takuhisa Nukaya1, Kiyohito Ishikawa1, Takuya Sadahira2

  • 1Department of Urology, Fujita Health University School of Medicine, Toyoake, Japan.

International Journal of Urology : Official Journal of the Japanese Urological Association
|June 24, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Robot-assisted radical prostatectomy (RARP) shows low perioperative infection rates. Shorter antibiotic prophylaxis (≤24 hours) with cefazolin or second-generation cephalosporins appears sufficient, alongside preventing bowel injury and managing catheters.

Keywords:
perioperative infectionprophylactic antibioticsrobot‐assisted radical prostatectomysurgical site infectionurinary tract infection

Related Experiment Videos

Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Area of Science:

  • Urology
  • Surgical Oncology
  • Infectious Diseases

Background:

  • Robot-assisted radical prostatectomy (RARP) is a common procedure.
  • Understanding perioperative infection risks is crucial for patient outcomes.
  • Antimicrobial prophylaxis patterns and their effectiveness require evaluation.

Purpose of the Study:

  • To assess the incidence of perioperative infections following RARP.
  • To analyze antimicrobial prophylaxis strategies used in Japan.
  • To identify risk factors associated with infections after RARP.

Main Methods:

  • Retrospective analysis of 6660 patients undergoing RARP (2009-2021).
  • Evaluation of cefazolin (CEZ), ampicillin/sulbactam (ABPC/SBT), and second-generation cephalosporins (2ndCPs) prophylaxis.
  • Assessment of surgical site infections (SSI), urinary tract infections (UTI), and remote infections (RI) within 30 days; logistic regression for risk factors.

Main Results:

  • Overall infection rates: SSI 1.2%, UTI 1.4%, RI 0.3%.
  • Superficial SSI was common; deep/organ/space SSI was rare.
  • No significant SSI difference between ≤24h and >24h prophylaxis. Bowel injury linked to SSI; high BMI, catheter issues, and ABPC/SBT use linked to UTI.

Conclusions:

  • Perioperative infection rates after RARP are low.
  • Prophylaxis within 24 hours, especially with CEZ or 2ndCPs, may be adequate.
  • Preventing bowel injury and optimizing catheter management can further decrease infection risk.