NEW METHOD OF TREATMENT OF PYOINFLAMMATORY SOFT TISSUE COMPLICATIONS IN PATIENTS WITH DIABETES MELLITUS
S Karatieieva1, I Plesh1, O Yurkiv1
1Higher State Educational Institution of Ukraine "Bukovinian State Medical University:, Chernivtsi, Ukraine.
Georgian Medical News
|May 9, 2017
Summary
Ozone therapy, using ozonated saline, showed no adverse effects on hemostasis or blood chemistry in patients with diabetes and infections. This treatment may improve outcomes for these complex cases.
Area of Science:
- Biomedical Science
- Clinical Medicine
- Oxidative Stress Research
Background:
- Diabetes mellitus and purulent-inflammatory complications present significant clinical challenges.
- Oxidative stress markers are crucial in evaluating disease progression and treatment efficacy.
- Assessing the impact of novel therapies on these markers is essential for patient care.
Purpose of the Study:
- To evaluate the effects of ozone therapy on oxidative stress markers in patients with diabetes mellitus and purulent-inflammatory complications.
- To assess the safety of ozone therapy concerning hemostasis and blood biochemical parameters.
- To determine the potential benefits of ozone therapy on treatment outcomes.
Main Methods:
- A study involving 124 patients with diabetes mellitus and purulent-inflammatory complications.
- Patients were divided into two groups: a study group receiving ozonated saline intravenously plus conservative treatment, and a control group receiving conventional therapy only.
- Evaluation of peroxide oxidation of lipids, protein oxidative modification, antioxidant protection, and toxicity markers over a 6-15 day period.
Main Results:
- Ozone therapy did not induce negative responses in hemostasis parameters.
- Biochemical blood characteristics remained unaffected by the use of ozone therapy.
- A favorable effect on treatment outcomes was observed in the group receiving ozone therapy.
Conclusions:
- Intravenous ozonated saline is a safe therapeutic option for patients with diabetes and purulent-inflammatory complications.
- Ozone therapy may offer a beneficial adjunct to conventional treatment, improving patient outcomes.
- Further research into ozone therapy's role in managing complex inflammatory conditions is warranted.
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